Common Symptoms of Kidney Disease


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Normally, the main complaint that is often felt by sufferers or people who suffer from kidney disease are the minute when they get exhausted quickly, feeling nauseous, as well as having a dry mouth. This condition, in fact, is caused by a decrease in the levels of sodium within the blood because the kidneys no longer can control the excretion of sodium. In most extreme cases, the impact can create further damages such as both arms and legs are becoming swollen, by which damage of this progressive disease will make those sufferers gradually unable to get up and just simply lying down on their bed.

In addition to the lack of sodium levels, the impaired kidney function is also resulted due to the rise in the potassium levels in the blood. As a result, this has led to a rise in levels of potassium which makes the muscles cramp and twitchy. Additionally, a high level of potassium can also affect further the heart muscle which is more dangerous. So, that is one of the reasons why people who are suffering from kidney disease can die from a heart rhythm disorder which is triggered by a high level of potassium.

Actually, it is very common to notice the fact that people who are suffering from kidney disease often feel sore due to the release of calcium from the bones just to compensate for a decrease in the levels of calcium within the blood. Perhaps, this condition is accompanied by an increase in the levels of phosphorus within the blood, by which it makes their bones becoming fragile and easily broken. Such an increase in the levels of potassium and phosphorus, additionally, occurs because of disturbance in the electrolyte balance which is due to the kidneys can no longer regulate the consumption of meals.

Furthermore, other complaints such as tingling and cramps can literally occur due to the nervous disorders because of toxic ureum that affects the nerves system. As for the other complaints such as experiencing complaints of nausea, the people who are suffering from kidney disease would end up losing their appetite. Therefore, the typical condition like this is generally caused by the rising levels of wasteful substances which make that toxic ureum resulting in metabolism of proteins that contains nitrogen.

Next, when talking about protein from more medical perspectives, it is actually a series of amino acids which is linked by peptide bonds (NH2). So, when this protein is cleaved into energy source regardless whatever sufferers’ condition, the NH2 will turn into NH3 (ammonia). Ammonia is a substance which is very toxic to the body. Therefore, patients' heart who suffer from kidney disease immediately change into a not so poisonous ureum, yet, the changes are disposed and remain through their ureum kidneys.

Apart from that, such a decrease in the renal function can further lead to the rising levels of toxic ureum in the kidneys. From medical viewpoint, if the kidney function is impaired, then the creatinin and uric acid will also get increased. Both of these compounds are derived from the protein of tired muscle tissues, where creatinin comes from creatine (i.e. one form of energy in the muscles), while the uric acid is derived from the purine which is an important component in the muscle cells. Normally, human muscles are becoming fatigue due to the overwork or excessive physical activities which naturally causes a decline in the renal functions. Therefore, all of these impacts make the sufferers of kidney disease feeling more nauseous and not having any appetite.

Meanwhile, the condition of anemia in the case of kidney disease can also make the sufferers having complaints when they feel shortness of breath and palpitations in their heart. Well, some of us may already know the fact that anemia occurs due to the decrease in the levels of hemoglobin within the blood. By the way, hemoglobin is a substance which carries oxygen, and it is naturally found in the red blood cells.

Hemoglobin can be reduced if the formation of red blood cells is disrupted. So, the reduction in the number of red blood cells is naturally caused by a decreased production of erythropoietin. Erythropoietin is a hormone which is in charge of stimulating bone marrows in order to make red blood cells. So, in the case of people who are suffering from kidney disease, their red blood cells generally can only last for 120 days (approximately three months). After that, they will be replaced by the new red blood cells; any changes in red blood cells requires the existence of erythropoietin. So, if there are any disorders causing a decrease in the renal function that creates low production in the erythropoietin, then those people who suffer from kidney disease may have further troubles when they think or concentrate on something.

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