In general, Diabetes is a disease which is caused by the high levels of sugar (glucose) in the blood, either due to a reduction of it or lack of insulin in the body. Such a high glucose level, in fact, can interfere with the structure and function of the blood vessels. Fortunately, there are some diabetics (people who suffer from diabetes) in general tend to have low levels of insulin; resulting in the occurrence of metabolism of carbohydrates, abnormal fats and proteins. 

Actually, the small blood vessels in the kidney organs over the time will eventually be damaged. Diabetes is by far one of the causes of occurrence in the kidney disease. The high level of sugar that diabetics possess in their blood, for example, can literally lead to suffer from kidney damage. Hence, the term used for both diabetes and kidney complications in which they relate to one another are called nephropathy.

First of all, diabetic nephropathy is a kidney function disorder due to the leakage of blood filter. Basically, the human kidney organ composes millions of filter units or neurons. Each unit has a filter or membrane part called the glomerulus. Additionally, the high levels of blood sugar will slowly damage those filtering functions.

Second of all, when the kidneys function properly, the condition of neuron proteins in the body moves steadily. The high blood of sugar levels will react with the protein, so as to change the structure and function of cells, including the basal membrane of the glomerulus. As a result, the protein will get damaged and this will cause the amount of leakage into the urine. To put it in a simple term, when the body undergoes kidney damage, the great amount of protein will be released out of the body through the urine and this condition is called albuminuria.

Technically, one of the functions of the kidneys is to remove the liquid impurities through urine protein levels as well as keeping the body stable. However, when the kidneys are damaged, then the situation happens reversely is the protein secreted through the urine and liquid waste, thus, will settle in the body. Therefore, the early sign of kidney disease symptoms in a person's body in which the albumin in the urine has been detected is also called with micro-albuminuria (the occurrence of micro-albuminuria which is characterized by the discharge of 30 mg of albumin in urine per day where the more protein is released out with urine, the more likely the condition of kidney potentially ends up in a chronic stage).

Hence, if a kidney sufferer is left unchecked, then the condition mentioned above will continue until the occurrence of kidney failure. After all, people who suffer from diabetes are strongly advised to check their levels of micro-albuminuria annually.

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